I wonder if these airplanes are using helium to "reduce the weight"... that is something I also don't usually on drones. Probably too expensive.
Filling a wing with helium would barely shift the weight of the plane measurably. Filling the cabin and cockpit would be bad for what I hope are obvious reasons...
I'm not an engineer, probably it is more reasonable to fill the remaining space with battery ;)
Also, helium requires airtight containment - which itself would add weight.
Not belittling you; trying to explain the problem better for you.