I don't think even Cloudflare bothers with this waste of time. If they did, they would certainly not have built their global infrastructure on JavaScript running on V8. They'd have done what Google and old-time Facebook did and built their whole infrastructure on low-level system languages, and hiring the world's leading minds on the subject to milk the last drop of performance from their hardware.
Even Google stopped to look at the problem and came up with Go. Not V8.