> So, if I am to start a new JS or TypeScript project or whatever, what should I choose and why?

NodeJS for the runtime if it's not in a browser, webpack for bundling. For the frontend stack, either React if you're in for a full application or, fuck it, good old jQuery if you don't want to do type document.queryXXX all the time. You'll find a ton of developers and coding bootcamp graduates to deal with all of that, and the AI agents should all be trained well enough on them.

Everything else is just a recipe for getting rug-pulled or being the bananaware customer responsible for the ripening.