Not "never again", it would be extremely difficult but science and math are also built on random, trial and error, and intuitions that could not arise from AI.
Computer can iterate without frustration on a completely random garbage. Once in a while it stumbles upon a gem. Even if it's one in 10000, that's still hundreds of good ideas in a day (provided enough GPUs).
You can generate completely random ideas (a couple proofs I saw where you define some weird set, pick an element and derive a contradiction when the set is empty or whatever).
Some of these will reach a conclusion: proof or a counterexample. And that's how speed can outperform creativity, if the speed bump is fast enough. It's the same as with those monkeys and Shakespeare.