Grace was in the US Navy in World War II. Even in our real history where Donald Trump was not President, Grace did not meet their strict requirements for women and so she was only able to get in via a special exemption. Can you imagine in the "Make sure our Warriors look good on TV" world of Pete Hegseth that they'd ever accept Grace? No, the Navy is for big strong men.
The Manhattan project would have been announced before it went anywhere, undermined during development and produced no real result. Japan would not have been nuked, but also would not have been invaded and the Pacific theatre would have in general developed in a completely different way. Without the American nuclear arsenal, the world may have skipped the cold war and nukes, or perhaps other states would have made them and used them in a heavy mutual bombardment without restraint.
Eventually in Europe, glasnost and perestroika would still have happened, and the USSR would still have fallen; but the geopolitical and economic importance of the USA would be little different to that of Brazil.