“Much as one cannot unhear a movie spoiler or a crossword clue, one cannot explore a problem as profitably and richly once one is aware of an existing solution.” He mourned, he added, “the path not taken, and the opportunities lost in the frantic race to develop this technology.”
This observation is so important. There is unintendedly something being taken away from us that cannot be given back. And it's a pure loss, there is nothing returned to us on an experiental level. It already existed before that "somebody else" would solve or discover something. Now this "somebody" is just just an alien nobody can relate to. And that "something" is everything.
Even if AI solves ageing, and climate change and whatever else; as humans we'll have lost something beautiful and precious. There will just be less of this sense of wonder and curiosity.