Run too big of a deficit = become miserable = blame dieting and stop halfway. Simply pick a deficit you can continue for long; it's the solution!
Average woman may have TDEE around 1800-2000, she can eat 1700-1600kcal comfortably.
You know that if i remove 150kcal from your diet, your wouldn't notice? that's like 2 slices of bread. So the hunger suppression will never be a question for vast majority of fat people
150kcal deficit over a year = 7.1kg or 15.6 lbs lost! and 300kcal = 31.2lbs or 14.2kg!! all this without any injection or drug without any exercise or severe loss of lean masss