Not at all. The app that is enforcing the change is a privileged Google app. Even if someone tried installing it on GrapheneOS, it wouldn't be able to do anything like remove apps, block installation, or disable apps.
Honestly at this point, I'm just gonna start transitioning to Ubuntu Touch. The Android experiment has run its course.
The narrative that GrapheneOS is so focused on security that it affects usability, especially given the context, is nonsense. The change that's being discussed here doesn't affect GrapheneOS or other non-GMS operating systems. The only affected OSes are the ones that install Google apps with privileged permissions.
If you want to switch to something else, go ahead. GrapheneOS is still a better overall choice.
On stock OSs, google signs major portions of the OS and is highly privileged, which is impossible to sidestep.
Optional is obviously easier than impossible.