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I take it for RA, and am kind of amazed I've not had any real side effects per se. Daily Folic Acid (which I take) is supposed to help. I take it once a week (20 mg). And was also kind of surprised when I started reading up on it what it also was used for.

It's used for any immuno related disease, it's crazy how many things it's used for.

Psoriasis, eczema and psoriatic arthritis being three that maybe you wouldn't think of when someone brings up methotrexate.

it was originally a chemo drug that was expanded to rheumatoid arthritis. nasty stuff