Well, that's OK, then.
What is the exact number when it's no longer acceptable? Is is 1,001? 10,001?
Exactly how many deaths are perfectly fine in the name of progress? How many people are we allowed to kill for the sake of convenience?
Currently the yearly global death toll for cars is at 1.16 million and climbing
No need to compare. Both can be bad at the same time.
Traveling the same distance without rail or air (i.e. on foot, horse, car) is also relatively deadly and the alternative (of living in small communities and not traveling long distances) is also not great for multiple reasons
You’d have to calculate how many lives speed saves. How many people had an organ delivered just within the safe transplant time? How many people were able to eat because a grain shipment could be diverted after a bad harvest? How many people didn’t contract cholera, because it takes minutes to manufacture pipes?