As long as you stick close to first-party defaults, you can circumvent almost all of that. I've had far less trouble with build steps in SPAs that follow this philosophy, than with most native environments. It only becomes an issue if you need to layer tons of individual dependencies for things to work.

I also stay away from dynamic prerendering and/or hydrating. If an SPA can't be hosted statically, it should have a very good reason.

IMO building around Vue has really paid off over the last decade. They fixed the frequent Webpack config issues with Vite, they fixed the frequent Jest issues with Vitest, they improved build times a lot with Rolldown and oxc, they fixed all the annoying linter/formatter config stuff with oxfmt & oxlint, and Vue itself prevents tons of issues that plague React projects.