Mathematics models the world, it does not have substance. It is a useful way of looking and a useful way of manipulating, but many models are equally useful. Capital T Truth, beyond models is very difficult to get at. We can show that things are true for certain models well enough. Showing that something is true in all models (a universal truth) is far more difficult. You face incommensurability.
I see a lot of people in technology fall into this extremely basic logical fallacy called Reification constantly.
I mean, when you really get down to it, either the particles and such operate on very specific rules, and the rules govern how all our brain and body work. Followed to the conclusion, the universe is computable and we can simulate life.