If you are going down this path, MI350P and RTX PRO 6000 Blackwell is what you would want. A lot more compute a lot more vram bandwidth.
But this gives you significantly more memory capacity for a compute/vram bandwidth tradeoff (i.e. arithmetic intensity) that's ultimately comparable to Blackwell, perhaps even more skewed towards compute. This seems good if you care about being able to store larger sparse models and more KV caches because that ultimately bottlenecks your ability to do inference.
https://www.servethehome.com/the-amd-instinct-mi350p-is-a-hb...