I'm interested to see what changes they end up implementing. For such a respected guy, I've always been surprised that Squidoo was his project. I rarely see Squidoo lenses in search results that amount to more than filler content and affiliate links, although to be fair I've also taught myself not to click on them. I know of a few websites that automatically flag Squidoo links in user profiles because it's so frequently used by spammers. Not a dig on Squidoo, I'm just curious what route they'll take to drop that reputation.
Seth contends that designers must see their skill set in a new light - as 'visual catalysts' in the growth process rather than mere web designers. I think he's right - we need to re-imagine and broaden the roles of designers and developers to be architects of growth rather than just code or logo monkeys.