Learn something new every day. I've always used Helvetica on all my web pages at the behest of my design co-worker. He's a print designer so it makes sense now.
On Windows, however, Helvetica isn't (at least from my experience) as nicely hinted, or at least doesn't play quite as well with Microsoft ClearType. And that's if it's installed, which is less likely on Windows. In that case, if your font stack specifies a fallback to Arial, which is ClearType's best friend, you'll probably be fine.