IMO, the Flask example is pushing it - considering how large a job rendering a template is, the number of customization points is probably appropriate, but at some point you're going to get lost in a rabbit hole of wrapper functions that call wrapper functions and end up with three equally appropriate levels you might hook into because the code was written to keep you from having to duplicate a single line of code from the library in your alternative implementation-- never mind how confusing that makes things to the casual debugger (who wants to get to the actual meaty code to see what's wrong with it). Flexibility is useful, but it must justify the loss of simplicity.
But yes, in the JSON cases, having more flexibility than a single 'loads' is clearly justified.