you can also read what happens when you take it too far
http://www.freeleonardpickard.org/Skinner-Timeline.html
http://www.dallasdancemusic.com/awareness-politics/73509-tee...
http://www.vice.com/read/life-is-a-cosmic-giggle-803-v18n5
of course rumor has it he would take DMT via IV for 8 + hours several times a week. I can only imagine what that would do to someone's mind (hint it wouldn't be pretty)