Untouchable algorithmic integrity? History tracking? Data not easily corruptible by users? Accuracy in decimal amounts past 12 to 14 significant digits, particularly if fractionals involved? Huge data volumes? Mind-numbing repetitive tasks?

Excel for that? No. Code for that? Yes.

Agility? Quick checksums? Looking for errors? Ad-hoc analysis?

Excel for that? Yes! Code for that? Depends on whether I have to do it again, or if it gets big.

Ad-hoc correlations for equality checking? I'll take a FULL OUTER JOIN over criss-crossing cranky VLOOKUP(...)s any day.