Yes! This has been a huge win for me.
I'd typically fall asleep at my desk around 3pm, or be fighting micro-sleep episodes. In any case, sitting there felt like torture. Never mind the effect on coding and debugging. Been doing that for decades. Tried ADHD remedies, etc. etc.
I started using a machine on a Friday, and noticed that although I was still a bit tired, I didn't take my usual 2-hour afternoon naps on the weekend. With the initial settings, I would still get a bit tired by mid-afternoon on a work-day, but it was an improvement.
After a second sleep-study and further calibration, I don't get tired at all in the afternoon. This is going to bed at 11:30 to 12:00 and waking up at 6:30 to 7:30.
It's hard to describe the practical effects of sleep-deprivation on programming effectiveness. It's like every programming problem just got a bit easier, and every tool just works a bit better. The difference between being slightly too dumb to do the job well, and being a monster is a small one.
Unanticipated benefits are that colds are not really tiring, and my alcohol tolerance is back to University levels (not sure if that's a win). On the flip side, I'm less inclined to drink alcohol, because I don't want to mess with my new mental powers.