On a new Lenovo laptop, the configuration hackery was rather limited:
- disable UEFI and use BIOS
- install Debian (wireless didn't work during the installation, but worked without a hitch afterwards)
- copy-paste a script for decent powersaving settings (might have worked out of the box with KDE or GNOME, but I don't use desktop environments)
The only thing which does not work at the moment is most of the special function keys, which is no big deal for me as I don't really use the functionalites anyway.