Ok, maybe not even almost every major idea (I did use the word "almost"), but pretty much by definition every major conceptual shift, from a round earth, to relativity, to microorganisms.
> Scientific ideas tend to me testable. A lot of what this guys suggests is entirely unfalsifiable. He may as well be discussing Pastafarianism.
Scientific ideas do tend to be testable. This doesn't mean we can't have ideas that are not testable or not yet testable. Hopefully, every idea will some day be falsifiable, but we can't rely on that. We may need to speculate in untestable territory before we find a plausible and reasonable theory that is testable. And as you know, science does not tell us that anything is true, only that some things can't be proven false.
There is more to life than testable scientific understandings. I could love my mother or I could not love my mother. Can you test that? Because you can not test it, does it mean it should not be mentioned and is not important?
Human love, creativity, and consciousness are perhaps the most interesting and important parts of existence, yet they are not currently testable from an experiential viewpoint, and they may never be.
There are qualities of the consciousness, which by definition are qualities of existence - love, color, taste, beauty, suffering, pain, joy - which can only be explained scientifically in their mechanical reflections in brain matter. Science can not tell us anything about the qualitative conscious experience of these qualities are, yet those qualities may be the most important part of the universe. What would the universe be without the conscious experience of its wonder and beauty?