I've had a recent incident in which Chrome was consuming about 7GB of memory, just because I had about a hundred tabs open! It was really, really, insane. This reckless disregard for memory usage caused more problems in terms of performance, and it wasn't apparent what was happening until things started OOM'ing. (Swapping is really just as bad as an OOM - the computer's practically useless if it's trashing due to low memory.)
Your ideal situation of having more memory used will, in many cases, lead to degraded performance.