It's great to see Node mature. When it first came out I was among the many people who said "That's neat.", played with it a bit and moved on.
But I wanted to make a meeting agenda site, since I don't like any of the ones out there right now. So the last 4 days I worked on one writing it as a JS web app that talks to a Node backend. It was quite painless. Anything I wanted to do (whether generating uuids, date formatting, etc.) there was a module available on npm. Couldn't be easier.
The platform has really matured a lot, and I didn't run into any issues with Node itself.
If you haven't yet, the next time you're doing an experiment, give it a try. I will probably write my next project this way too.