Depression seems to be defined (or at least is talked about like) a set of symptoms. As far as I can see, it's like the observed state of data corruption: there are many, many things that can cause that, some being an order of magnitude easier to fix than others.

Sometimes people feel horrible for a real reason, but don't know why. It would be foolish to medicate that away.

What if the chemical imbalance is a symptom of depression, and not the cause?

I've been stuck at that stage of thinking as well, and after many data points that got shunted aside. Currently the most interesting and fun counter point to it I am using is that its not just "mind", but a mind-body issue.

There are many ways in which your body function influences and alters mood and perception, and vice-versa.

Talk therapy goes the other way too, it has the potential to alter the equation, provided other things are done as well.

Going to back that up at all? I believe in unicorns, by the way.

Obviously brain chemistry is involved (reduced serotonin, etc.), but I'm sure I could adjust your brain chemistry by jumping out at you and saying boo too; so I don't it follows that chemical intervention is the only approach that will change your brain chemistry.

I think antidepressants are very important and a great tool if you are suffering from severe depression, but I don't think they are the only answer nor a long-term solution, alone.

As an e.g. a metastudy on CBT - https://www.sciencedirect.com/science/article/pii/S027273580... - indicates that it is both effective and superior to antidepressants alone.

Given the nature of depression, which really muddles your mind clear advice is vital - go see your doctor, get onto antidepressants (you don't have to be on them forever), get onto a form of therapy. The shit works.

Exercise is a chemical intervention. It is not a panacea and it will take time, typically weeks before it has a significant effect, but it does have an effect. The body is the temple of the soul, you should not ignore either.

Chemical imbalance just means a chemical level associated with feeling bad. Which is also what psychological pain is. So you will you need to be more specific if you want to differentiate.