I haven't used any antivirus software in years, IMHO they're just annoying and reduce performance (used to use NOD32 until 2007, loved it back then). Here is what I do instead:
- surf the web consciously
- do not open any email attachments from unknown senders (seriously, it's 2013, who does that anymore?)
- do not open any URLs from unknown senders (same as above)
- disable unnecessary browser plugins (i.e. everything but Flash)
- use NoScript-like browser addons
- only run executables I 'trust' (tough one, I know)
- run executables I do not 'trust' in sandbox or VM
- properly configured router firewall settings
- * software firewall to monitor & block/allow incoming *and outgoing* connections (Comodo Firewall)
- * work with a user that does not have root/admin privileges (*Power User* privileges are sufficient for daily work)
Esp. the last two points are important and unusual. This requires a certain level of knowledge about IT, computers and some common sense, though.If I really need to check a file for malware I use webtools like http://virusscan.jotti.org