The short life and hard times of a Linux virus (2005)
librenix.com
librenix.com
For a recent account, see:
http://arstechnica.com/security/2013/04/exclusive-ongoing-ma...
It feels like something that you'd do just to err on the safe side.
It's checklist items like "run an anti-virus" that make "compliance" into a pudgy, flaccid, bad word.