To take an example the Capsicum people are fond of: Decompression. zlib has a long history of vulnerabilities in decompression of corrupt data, so it's a natural thing to run inside a sandbox. djb's argument is "but a vulnerability in zlib is still bad because it can return incorrect output", which is true as far as it goes, but it completely misses the important point that it prevents the attacker from accessing anything not inside zlib's sandbox -- say, connections to a database.