Most data isn’t "big" and businesses are wasting money pretending it is
qz.com
qz.com
You know who actually does "big data"? Physicists. There are some telescopes that generate terabytes of data per second. There are other scientific fields which generate very large, single data sets such as genomics, proteomics, climate, etc.
You might be storing multiples of that amount of data if you are doing a shotgun sequence assembly, or looking at polymorphisms, but then you're likely to have no more than 10 copies, and i can't imagine you'd have more than 100 copies. For the human genome, 100 copies would be 75 GB, which is still only about four times the size of Team Fortress 2.
But yes, the day will come when it's feasible to simply sequence and compare large numbers of genomes. But by the time sequencing technology has got that much better, so will computers have!
There are ~30k genes (encoded protein sequences).
100,000 human individuals may or may not have that many deltas per gene.
The data is naturally structured. There is no reason to believe that looking at 72TB at once is useful. You would start by looking for correlations with particular genes. (Even correlations with random genes is merely 30,000 simple problems.)
This kind of work can be done on a single multicore computer with a lot diskspace and memory, if you have the right tools.
Using "Big Data" as a noun to refer to actual data sets offends my grammatical senses.
In this case, you can substitute "data" with "information", and "most information isn't big" definitely sounds grammatical.