I worked with Visionect to create an interactive menu using their ePaper Development Kit[1]. The ePaper technology itself has refresh speed limitations, but great resolution & power-saving advantages. Their SDK exposes a JavaScript API for handling display refresh, which was easy to implement in Backbone.js render methods. You should try this if you want to build an MVC App[2] on an ePaper device.
[1] http://electronics.visionect.si/products-hardware/epaper-dev...