Besides the fact that most commercial monitors have pitiful ppi, the fact that monitor manufacturers are selling mostly widescreen monitors with a poverty of vertical room drives me crazy. It's hard to read a pdf of a book when its resolution makes it hard to fit a single page onto your screen. There is something about continuous scrolling that makes it harder for me to remember the text that I'm reading.

So a large screen e-reader (that won't have any backlight issues) could be a great gadget to have. I tried a Kindle DX in 2010, but I found panning around in PDFs to be too slow for enjoyment. If and when the technology improves enough, there could be a big student market for a large screen e-ink reader that can display PDFs (or saner formats, like DJVU).