I've often thought that in a warped, twisted way totalitarianism gives meaning to life for certain people. If it opression is so intense to make life worthless, then one has a cause dearer than life itself - to fight this opression. This struggle itself is meaningful. Many 'hero' movies are structured in this way, the 'good guys' have a cause, usually around defeating some kind of evil, that gives them ultimate purpose.

Likewise, I've found friends with far worse actual problems in the developing world to be existentially happier. They derive great pleasure in being able to go to a rock concert, etc. The game dynamics still work for the majority. Lots of intermediary issues to overcome, bosses to beat. Threat of destruction (socially or economically) seems to be wonderfully stimulating. Game dynamics still work.

What I find far worse is the banality of the first world. That seems to evoke and ferment existential concerns. Kind of along the lines of https://www.youtube.com/watch?v=98LeLZ2crZE

In a way, it is the problem one faces once more basic things are taken care of. Hard to focus on existential angst when hungry.

At the end of the day, even though the universe itself may be arbitrary and doomed, I found that the only things that infuse durable meaning into us as humans is our love for each other, our desire to understand this universe, and our appreciation of beauty in all its forms.