I've never understood the caps lock/control switch; swapping the ctrl and alt on one side of the keyboard just feels so much more natural to me: left thumb is alt, right thumb is ctrl.
Caps Lock to Ctrl (when pressed with another button) and Esc (when pressed alone) is one of the most efficient workflow optimizations I know of, even for regular computer use.
The usual plug (for OSX):
1. Set CapsLock to Control:
System Preferences
-> Keyboard
-> Modifier Keys...
-> http://i.imgur.com/joR19Hj.png
2. Get KeyRemap4MacBook: https://pqrs.org/macosx/keyremap4macbook/
3. Make this change: http://i.imgur.com/61lmhZ5.png>That's quite a reach, under your hand, which is trying to hit another key at the same time. Usually I use the modifier key with the opposite hand, so I don't run into this problem.