JPolite - is a lightweight front-end web portal framework based on jQuery.
code.google.com
code.google.com
Not, actually.
A surprisingly large part of my enterprise prospects/clients have javascript switched off completely, and a a large part of them still use IE6!
It is tempting to ignore a dinosaur client who is still on IE6, but when the dinosaur happens to be a top manager at a large bank -- that makes you think.
As a result I am minimizing/eliminating JavaScript and sticking to simple html forms. Hell, I even have replaced all PNGs with GIFs after a IE6 user complained he couldn't see the charts.
It is a pity, of course, but business users' environment is a bit different from consumers' one.
I've never been a fan of these full-JS layouts though, they chug so hard if the browser isn't Chrome!
Personally if I was gonna go for this kind-of JS framework thing I'd use EXT JS... http://extjs.com/products/extjs/