What I'd like to see is mass adoption of Jabber/XMPP, since it handles IM stuff, along with tons of other features. I think it could probably totally replace e-mail, since most servers and clients support offline messaging, so you can queue up messages even when you're not online. Also, imagine how everything would change if you used IM for password resets or signup confirmations, instead of having to wait a few minutes to get an e-mail with your info, it would be nearly instant.
Another cool possibility I see with Jabber mass-adoption is authentication. You could develop (if there isn't already) a way for people to login everywhere with only their jabber id, and then the site could just IM you to ask if it was really you who attempted to sign-in. This is a lot like OpenID, except I think alot faster and probably a lot easier to implement.