BOS has certainly made huge gains in biotech. BOS has more mid-size biotechs than SFO, but SFO has an edge in tiny, less than 10 person start-ups (but not by much).

The biggest difference between BOS and SFO are the big biotechs. SFO has one (GNE), while BOS many.

> Biotech ecosystem is better in BOS

That's debatable. I think Boston and the Valley are about the same (with the Valley maybe a little ahead) for biotech. Either way, Boston (as a city) is depressing as fuck, so I would avoid it like the plague.