I've written some marvelous code and completed gargantuan projects on my lonesome, battling thousands of lines of assembly and debugging hardware circuits and stuff.... and never used.
It's stupid to think your brain needs an external stimulus to be creative. You can be creative and withstand by just willing it - it's just not the easiest way out. When you take drugs you're either lying to yourself and pretending there is no harm in fucking up your brain - losing sense of priorities, time, yourself, and the world around you - or afraid of how it would feel without them.
Anyone can do anything without these drugs, and I'm speaking from experience. Staying up for 65 hours straight? Been there, done that with nothing more than coffee and cold showers. Write some brilliant hacks that do something genius in little lines of code? Check. Debug memory leaks and crashes across over 100k lines of C code going to and from different dynamically-linked libraries? Check. Writing your own OS Kernel? Check.
I pity those that feel you need drugs to accomplish, because that's just not true.