One of the most important musicians of all time. The Velvet Underground inspired countless musicians and greatly influenced whole genres of music, it's hard to see how Punk would have existed without the Velvet Underground.
Lou Reed's greatest contribution though was his ability to mix great song writing with artful experimentation. From ST with Nico to Loaded to White Light White Heat to Vicious and Metal Machine Music, Lou consistently wrote great songs and expanded the worlds musical pallet. He will be missed.