There are a lot of counter examples to this claim but just to keep this short, I'll go along with your claim.
A downside of this is heavy overload of keywords/symbols. For example, last time I checked, the underscore (_) has six different meanings depending on where it's used.
The number of syntactic rules is not a good way to judge whether a language is difficult to read, otherwise, Brainfuck would be the most readable language on the planet.