This means that we're going to need many more IP addresses in cases where we want to host multiple HTTPs sites. This is a problem because we're running out of IPv4 addresses and IPv6 support within the range of systems not supporting SNI isn't that reliable either.
This might not matter that much in the future, because larger sites should still have enough IPv4 addresses, but it will hurt smaller sites.
In my case, I can't possibly offer SSL for all of our customers (most of them are using their own domain names, so no wildcard certificates) as back when I only got 32 addresses and it's next to impossible (and very, very expensive) to get more nowadays.