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There's also Google's own version of trimmed down youtube: http://www.youtube.com/feather_beta

After enabling that I've never looked back. No comments and loads way faster.

This should be more well known. I just enabled it and don't plan on ever looking back.

Until you want to watch a playlist or a channel without choosing each video each time.

Feather Beta doesn't work with the "Play all" links or playlists in general.

I created a little thing for making and sharing playlists: http://www.cueyoutube.com/

I tweet my lists using the hashtag #cueyoutube which means I can always go back and find them later using http://snapbird.org/

This is the problem I ran into, I originally enabled it think it was great and the next day promptly disabled it because of this.

You're right, this is wonderful.