You have two real options here:

In Ear: On in ear, you should spent the extra money for custom ear molds. This will allow for all day comfort: http://www.sensaphonics.com/

If the headphones you are considering are not on this list, then I would not consider them. I like shure, but you can also get etymotic research.

Over Ear: Beyer Dynamic DT 770. Velour ear pads (for all day comfort and isolation)

I have owned: Shure E2C, E4C with custom molds, Shure 840, Beyer Dynamic DT 770, Bose TriPort (previous lightweight champion, but lacking on sound)

I have tested extensively: Audio Technica m50 (more base response), beats (too much bass), All kinds of sennheiser under $150, and various other brands under $200.