If you think about it in a results-oriented manner, in order to "vote her out," what is needed is an opponent whose strengths outweigh the forces keeping her in place. Next on the list of possibilities as I see them is to create a force of voice that she must listen to. I don't think an internet petition is as effective here (keep in mind that the vast majority of IPs have zero effect, so the odds are against this one), so the alternative is purchasing enough vocal power to drown out the lobbyists who have her ear and direct her toward unfavorable positions.
An ideological position based on the malleable concept of representative democracy is already on shaky ground, so putting oneself in her place, learning about her motivations, and playing to those will operate the machinery of predictable political action much more efficiently. "Know your enemy" is a better action-plan than "designate an enemy and say the same thing as you would with anybody else."
In other words, calling her a "cancer" isn't enough.