There was one Blackboard dashboard unit that allowed you to embed arbitrary HTML, and I injected some JS onto the page that allowed you to set a background image, made clicking on links pop open new tabs (instead of whatever abomination of javascript they had), and all kinds of other little tweaks. I even got most of the way through writing a drag-and-drop module rearranger before I graduated. Maybe 60% of what I knew about JS and CSS at the time I learned through trying to add features to Blackboard through script injection.
Naturally, I wasn't the only one frustrated at Blackboard, and the script travelled by word-of-mouth to a pretty sizable chunk of the school. At that point, it was probably the most widely-used thing I'd ever built.