1) Find out a few companies hiring in your area through deep research.
2) Contact a few people in these companies to get a lay of the land on the positions and the environment. In short, informational interviews over coffee. DO NOT ASK FOR THE JOB IN THIS STEP. JUST DON'T.
3) Your objective should be to see which jobs you'd like to do, and which jobs you can do. The intersection will go on your final list.
4) Keep contact with the coffee interviewees by sending them interesting links, or other 'gifts' and by that I don't mean basket of chocolates, I mean any valuable information/links/thoughts that could help them with whatever - business or personal. Reach out once right after meeting, once one week later, and once every month from here on.
5) Craft your Resume and cover letter focused on THE NEEDS OF THE HIRING MANAGER. Think of your resume as a story you're telling the hiring manager that resonates with him based on his needs.
6) Nail the interview .
If any step from 1 to 6 goes wrong, go back to the previous step and carry on.
Good luck. Oh and show your boss the finger when you walk out with a new offer for 10-20% more pay.