I have to disagree with your disagree! Many (most) jobs go through a pre-screen. The project manager is far too busy to filter all the crap, HR does that. HR sees a unfamiliar format, and simply bins that resume.

If they specifically allow other formats, or request a specific format, use it. But, in the case that they don't specify -- go with the most common format in the industry, anything else is nuts.

Additionally, if the primary filter on talent is .docx versus .pdf (or .txt or even .tex) -- it is a place so stupid you probably don't want to work there anyway.