Big Pharma Abusing Patent Laws To Seize And Destroy Legal Indian Generic Drugs
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Personally I would be looking for evidence of a thriving industry in novel therapeutics, rather than generics, before considering everything hunky dory after a ban.
Big Pharma uses their 'research costs money' argument to counter this, but they forget - conveniently - to mention that they spend a very large multiple of their expenses on research for the marketing department.
They abuse the patent system left, right and center in order to extend the income from so called 'blockbuster' drugs at the expense of doing something innovative for a smaller group of people.
Generics wouldn't stand a chance if it weren't for the price gouging going on.
http://www.google.com/finance?q=NYSE:MRK&fstype=ii
http://www.google.com/finance?q=NYSE:JNJ&fstype=ii
If you actually look at the numbers, you'll see that Big Pharma's operating expenses look much like Big Technology.
http://www.google.com/finance?q=NASDAQ:INTC&fstype=ii
http://www.google.com/finance?q=NASDAQ:GOOG&fstype=ii
Note: my 1-3 multiple is actually just the ratio of "Selling/General/Admin. Expenses, Total" / "Research & Development". It's a gratuitous overestimate, since marketing is only a fraction of "Selling/General/Admin. Expenses". That category also includes things like producing drugs, accounting, delivery, etc. But I'm too lazy to look up a more detailed balance sheet.
[edit: I'm curious, why am I being downmodded? All I did was provide some facts.]
Also there are large expenditures that are not directly in the marketing budget but that you would normally classify as marketing, these include seminars, promotional meetings with prescribers, lobbying activities and so on.
enjoy the read:
Incidentally, I'm pretty sure your $65k/year is not typical. That would be the equivalent of having one salaried employee spending 100% of his time selling to a single doctor.
You're right, it wasn't 65,000, it was 'only' 61,000... and no, of course it is not spent by sending a full timer to a single physician, but the net outcome of expenditure / target market is $61,000.
The figure came from this article:
http://www.plosmedicine.org/article/info:doi/10.1371/journal...
For comparison, Merck and Johnson and Johnson (the two drug companies I bothered to look up) spent $13k/doctor on R&D.
Incidentally, one of the bigger items included in marketing is free samples (totalling $16,800 per doctor), expensed at retail price [1]. That's basically just a giveaway from the drug companies to people doctors feel are deserving (usually low income/uninsured patients).
[1] The real cost is actually less, since the drug company would not necessarily get retail price if the drugs were not given away free.
Personally I found your contribution useful. It answered, at least roughly, a question I didn't have time to investigate myself: What ratio of marketing:R&D is considered acceptable?
Which it is is always a guess.
You say that like it's a bad thing. That's dodgy at best - telling doctors what a drug does seems like a very good thing. Telling consumers that there's a drug that might help with a problem that they have seems like a good thing. (They may not be talking to a doctor about it.)
However, let's go with "it just increases the numbers of people using it". If you're someone who needs that drug, increasing the number of people means that other people are helping to pay for the fixed costs. Since the "good" fixed costs are rather high, that's a good thing for you.
> They abuse the patent system left, right and center in order to extend the income from so called 'blockbuster' drugs at the expense of doing something innovative for a smaller group of people.
(1) There's no such connection. (2) What's stopping you from producing said "innovation"?
A lot of people are quite fond of criticising other people for not doing some "easy" good, yet the critics don't bother to provide said good.
This is interesting, because the domain is almost always one where "good" comes with fairly large financial rewards. If the critics are correct, they're not doing an easy good that would both provide them with considerable money (which they could use to do more good) and drive bad people out of biz.
I got the impression that the article was generally anti-patents and I framed my response in that context. A ban on patents has been beneficial for the generics industry but if it has a higher cost in terms of stifling novel therapeutics, which also have a benefit, then it may be an overall loss for the population as a whole. In this way there is little difference between a ban on patents being good for the generics industry and strong copyright laws being good for the record industry. Both may be true but the interests of the population may not be aligned perfectly with these industries.
On the other hand if research into novel therapeutics is able to thrive with a ban on patents then you get the benefits of new therapies and the affordable prices. This is what I would like to see before dismissing the patent system entirely when what may be best is a little tweaking.
Finally on marketing versus R&D I'm not sure that the multiple could genuinely said to be 'very large.' This article suggests marketing:R&D is 2:1. http://www.plosmedicine.org/article/info:doi/10.1371/journal...
That may seem like a little bit until you realize that there are roughly 500,000 such meetings annually (2008).
The spendings in that article account for only (roughly) 40% of total expenditure.
ok, here is a link: http://www.allbusiness.com/company-activities-management/fin...
From the same book quoted above, in 1990 it was roughly 1:3.2, since then the situation has improved a bit, but I can't find anything closer than 2004.
Still, it is quite shocking when you realize that most of the marketing goes towards pushing a few, well established drugs at immense markups, and that most research is focused on either extending the life of these drugs or the introduction of replacement drugs for drugs that are on their last legs in the patent cycle.
Genuine research (research which attacks problems for which no current solution exists) is a very very small fraction of total expenditure.
more interesting data here: (not sure if that link works...)
Not that I am defending Big Pharma, but the generic producers are profiting on research that they did not fund. It has a number of good effects sure, but I can understand why there are powers that find this unacceptable and want to stop it.
"Yes, we did that ?"
I hope the wsj is good enough for you:
http://online.wsj.com/article/SB124949598103308449.html
(google cache entry of the same link because of silly restrictions): http://74.125.77.132/search?q=cache:KQdnCYpa9HgJ:online.wsj....