This has got to be one of the most impossible to translate Spanish writing authors ever.
One Hundred Years of Solitude made me decide to improve my Spanish so I could read it in the orginal language. Still haven't yet :-(
My spanish is decent enough to have read a few of Marquez's books in the original language, but not good enough to appreciate them as much as I did in English.
I'd recommend starting with "El Colonel que no Tiene que Escribe". It was used in my AP Spanish class in high school and is short enough so you don't get frustrated with the slow going of reading in a new language.