Previous versions of Cryptol included backends for producing C and VHDL for higher-performing implementations on CPUs and FPGAs. Cryptol 2 is a ground-up rewrite and those backends aren't there yet, though we have plans to be working on new backends soon.
Cryptol is largely focused on issues of functional correctness. For power and timing attacks, you might want to build a C or Assembly implementation by hand that addresses those. However, what you're left with is fairly difficult to reason about on the level of functional correctness. We have another project, the Software Assurance Workbench, that builds formal models from LLVM and Java code. With this in hand, you prove equivalence between the hardened, high-performance implementation and the Cryptol specification.
Does that help clarify the role Cryptol might play in a cryptographer's workflow? Also, could you elaborate about your "how safe it is" question? I'm happy to answer :)