It was a colossal pain in the butt using USB in mobile robots like we did at Anybots. There aren't compatible locking versions of the connectors. Ethernet/RJ45 is much better without requiring thumbscrews.
I think I have more RJ45 cables with broken tabs than ones with the tabs intact. And trying to keep RJ45 in place without the tab is hopeless.
Surely you could build some sort of retaining clip for a usb cable is you had to?