I am a tad perturbed that a quick skim didn't present to my eyes any statements along the lines of "But we never tried it, at all, so take it with a grain of salt."
Either that or I somehow completely missed the table showing the effect of the schedule on subjects vs. controls, or any other sort of experimental confirmation whatsoever.
To be clear I don't object to the analysis or its methods, I object that it's not being clearly confessed to be an analysis in bold letters.